Product introduction:
CAS: 936563-96-1
MF: C25H24N6O2
Loss on drying: ≤1.0%
Purity: ≥99.0%
Description: Purity 99% Ibrutinib powder cas 936563-96-1 is an inhibitor of Bruton tyrosine kinase (BTK) for the treatment of chronic lymphoblastic leukemia (CLL) and sleeve cell lymphoma (MCL).
Application:
1. Purity 99% Ibrutinib powder cas 936563-96-1 is used for Chronic graft-versus-host (cGVHD) disease after failure of one or more prior lines of systemic therapy.
2. Chronic lymphocytic leukemia (CLL) who have received at least one prior therapy.
3. Mantle cell lymphoma (MCL) who have received at least one prior therapy.
4. Marginal zone lymphoma (MZL) who require systemic therapy and have received at least one prior anti-CD20-based therapy.
5. Waldenstrom’s macroglobulinemia
Certificate of analysis
Items | Standard | Results | |
Description | White To off-white powder | White powder | |
Solubility | Soluble in tetrahydrofuran, slightly soluble in methanol,
dichloromethane or acetonitrile, slightly soluble in toluene, practically insoluble in water |
Conforms | |
Identification | Should be accaordence with reference | Conforms | |
Water | ≤1.5% | 0.05% | |
Solvent
residue |
THF≤720ppm | 400ppm | |
Methylbenzene≤890ppm | not detected | ||
Methanol≤3000ppm | 30ppm | ||
Dichloromethane≤600ppm | 250ppm | ||
Ethyl acetate≤5000ppm | not detected | ||
Residue on ignition | ≤0.2% | 0.07% | |
Heavy metals | ≤20ppm | Conforms | |
Related substances | Single impurity | ≤0.2% | 0.04% |
Total impurity | ≤2.0% | 0.27% | |
Assay | 97.0%—103.0% | 100.4% |
FAO
Q1: Can I get some samples?
A: Yes, we can supply the free sample, but the shipping cost be paid by our customers.
Q2: How to start orders or make payments?
A: Pro forma invoice will be sent first after confirmation of the order, enclosed is our bank information. Payment by T/T, Western Union or , Remitly.
Q3: How to confirm the Product Quality before placing orders?
A: You can get free samples for some products; you only need to pay the shipping cost or arrange a courier to us and take the samples.
Q4: What’s your MOQ?
A: Our MOQ is 1 kg. But usually, we accept less quantity such as 100g on the condition that the sample charge is 100% paid.
Q5: How to contact us?
A: You can chat with us by WhatsApp, Telegram, Signal, Skype Line, or WeChat. You can choose your interested products and send an inquiry to us. You can dial our telephone directly; you will get our reply. Email us.
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