Arbidol HCl Powder CAS 131707-23-8

Product name:
Arbidol HCl Powder CAS 131707-23-8

Arbidol HCl powder cas 131707-23-8 inhibits the cell entry of HCV pseudoparticles of genotypes 1a, 1b, and 2a in a dose-dependent fashion


Product introduction

Cas: 131707-23-8

Other names: ARB, Arbidol, Umifenovir hydrochloride

MF: C22H26BrClN2O3S

Molecular Weight: 513.87544

Appearance: White or off-white crystalline powder

Residue on ignition: ≤0.2%

Assay(HPLC): 98.5%

Description: Arbidol HCl powder cas 131707-23-8 (Umifenovir) is a broad-spectrum antiviral compound that blocks viral fusion, used in treatment of influenza and other respiratory viral infections.

Application: Arbidol HCl powder cas 131707-23-8 inhibits the cell entry of HCV pseudoparticles of genotypes 1a, 1b, and 2a in a dose-dependent fashion.

Arbidol HCl powder cas 131707-23-8 also displays a dose-dependent inhibition of HCV membrane fusion, as assayed by using HCV pseudoparticles (HCVpp) and fluorescent liposomes.

Arbidol HCl powder cas 131707-23-8 is found to present potent inhibitory activity against enveloped and non-enveloped RNA viruses, including FLU-A, RSV, HRV 14 and CVB3 when added before, during, or after viral infection, with IC50 ranging from 2.7 to 13.8 mg/mL.

Arbidol HCl powder cas 131707-23-8 shows selective antiviral activity against AdV-7, a DNA virus, only when added after infection (therapeutic index (TI) = 5.5).

Arbidol HCl powder cas 131707-23-8 induces changes to viral mRNA synthesis of the PB2, PA, NP, NA, and NS genes in MDCK cultures infected with influenza A/PR/8/34.


Arbidol hydrochloride (ARB) is a small monocular compound used as a broad-spectrum inhibitor of influenza A and B virus, parainfluenza virus, respiratory syncytial virus, adenovirus, coxsackievirus and hepatitis C virus infection. It is less likely to induce drug resistance than other compounds, such as adamantine and oseltamivir. However, its mechanism is complicated: earlier reports indicated that ARB could inhibit the membrane fusion of enveloped viruses in vitro and strengthen the interactions between virus glycoprotein and the membrane of host during the endocytosis. However, this scenario cannot explain the antiviral activity of ARB on non-enveloped viruses that directly release genomes into the cytosol without a membrane fusion process14. Moreover, a recent study has found that ARB exhibited only 6% to 8% inhibition of IFV viral fusion from measurements of hemolysis analysis in vitro. It seems that the antiviral efficacy of ARB does not completely depend on the anti-fusion activity.

Other chemical names: Arbidol hydrochloride hydrate, 6-Bromo-4-[(dimethylamino)methyl]-5-hydroxy-1-methyl-2-[(phenylthio)methyl]-,1H-indole-3-carboxylic Acid Ethyl Ester Hydrochloride

Certificate of analysis

Items of analysis Standard Result of analysis
Description White or creamy or siskin-green crystalline powder Conforms
Solubility Slightly soluble in chloroform and 96% ethyl alcohol, practically insoluble in water Conforms
Identification IR Conforms
UV Conforms
Should show positive reaction of chlorides and bromides Conforms
Related substance Single impurity ≤0.5%

Total impurities ≤1.0%



Moisture content 3.0%~~4.0% 3.7%
Residue on ignition ≤0.1% Conforms
Heavy metal ≤10ppm Conforms
Residual solvents Acetone NMT 0.4% 0.02%
Assay 99%~101% 99.6%



Q1: Can I get some samples?
A: Yes, we can supply the free sample, but the shipping cost be paid by our customers.

Q2: How to start orders or make payments?
A: Pro forma invoice will be sent first after confirmation of the order, enclosed is our bank information. Payment by T/T, Western Union or , Remitly.

Q3: How to confirm the Product Quality before placing orders?
A: You can get free samples for some products; you only need to pay the shipping cost or arrange a courier to us and take the samples.

Q4: What’s your MOQ?
A: Our MOQ is 1 kg. But usually, we accept less quantity such as 100g on the condition that the sample charge is 100% paid.

Q5: How to contact us?
A: You can chat with us by WhatsApp, Telegram, Signal, Skype Line, or WeChat. You can choose your interested products and send an inquiry to us. You can dial our telephone directly; you will get our reply. Email us.


There are no reviews yet.

Be the first to review “Arbidol HCl Powder CAS 131707-23-8”

Your email address will not be published. Required fields are marked *

Shopping Cart